Mifepristone Misoprostol

A Guide to Mifepristone and Misoprostol: What You Need to Know

Mifepristone & Misoprostol are medications that can be used to cause an abortion. It should be used 63 days after beginning a woman’s last menstrual period. It is sold under many trade names worldwide and was formerly called RU-486 when it was in development.

They work by blocking the hormone progesterone, which is needed to sustain a pregnancy. The body makes progesterone during the first trimester of the pregnancy. Mifepristone and Misoprostol are safe and effective medications that can be used up to ten weeks after your last menstrual period or within seven weeks of conception.

How does it work?

Misoprostol or Cytotec is a prostaglandin used to induce labor and cause an abortion. It works by causing the cervix to soften, thicken, efface, and dilate. Mifepristone blocks the action of progesterone needed to maintain a pregnancy. The combination of misoprostol and mifepristone is 93-96% effective during the first 50 days of incubation.

Mifepristone is used in conjunction with misoprostol to bring about abortion up to 63 days after beginning a woman’s last menstrual period.


Doctors recommend misoprostol 800mcgs as in 4 tablets of 200mcg, which should be inserted vaginally as vaginal insertion is more effective than oral.


Mifepristone 200mg can cost you around Rs.304, and misoprostol 200mcg can cost around Rs.15.80.

What is abortion?

The intentional termination of a human pregnancy is known as abortion. In many parts of the world, women resort to abortion as their only viable option to control the number and spacing of their children. However, unsafe abortions lead to death every year. In 2015 alone, 418000 women died from complications related to pregnancy or childbirth; an additional 5 million experienced severe health issues and disability due to complications from unsafe abortion.

The decision to get an abortion should not be taken lightly, but sometimes it is the right choice. The following are some of the main reasons why you might choose to have an abortion:

  • If the baby inside has been diagnosed with a fatal condition
  • If the baby is a danger to the mother’s life and will not survive
  • If the woman was conceived after being raped

Several people choose abortion in many nations because they prefer a baby boy and wouldn’t want a baby girl. Abortion is banned in many countries and is only performed for the reasons stated above.

What is an unsafe abortion?

According to the World Health Organization, “a procedure for ending a pregnancy performed by persons lacking essential experience or in an environment lacking minimal medical standards.” Abortions that are not safe are a leading cause of maternal death and morbidity worldwide.

A recent study showed that around 47,000 women die from unsafe abortions in the developing world each year. Unsafe abortion can be defined as a process for terminating a pregnancy by persons lacking the required skills or in an environment not fit for this purpose. There are many reasons it occurs: lack of knowledge about contraception and safe abortion methods; restrictive laws and policies; stigma surrounding abortion; lack of access to family planning services and trained providers.